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德國Bio-Sys GmbH
Bioreader是一種用于ELISPOT斑點計數的科研用儀器，它的出現解決了ELISPOT斑點計數的快速化，標準化和斑點信息的詳細化，并且可以對細胞因子進行半定量分析。

德國Bio-Sys GmbH公司介紹：

l 具有20多年的生物圖像分析儀生產經驗

l 十年的ELISPOT圖像分析儀生產經驗

l 在全世界廣泛使用和認可

l 1997年推出第一代Bioreader 1000型和2000型ELISPOT圖像分析儀

l 2001年推出BioReader 3000型ELISPOT圖像分析儀，獲得應用于ELISPOT斑點識別的3D雙光源專利技術，首次實現對ELISPOT膜板和ELISPOT透明板的良好識別

l 2004年推出BioReader 4000型ELISPOT圖像分析儀，第一個采用改進機械結構的前置式載物臺和自動開關密閉檢測室，同一孔中同時識別多至三色ELISPOT斑點

l 2004年底推出BioReader 4000-F型熒光ELISPOT圖像分析儀，首次實現熒光ELISPOT檢測

l 2007年推出Bioreader 5000型，在軟硬件自動化和易用性上獲得提高

歐盟科技項目：Eureka Project 2956（多種細胞因子分析儀）指定儀器

BIO-SYS’ Bioreader’s and Biocount’s are in world-wide use for pharmaceutical research and quality control, immunology, microbiology and genetic toxicology (biomedical and routine). Our systems purpose is to automate tedious counting routines to speed up procedures and get the researcher fastest access to their information and results.

Several large Research-institutes are using BIO-SYS-Instruments to develop faster and more efficient routines.

Frauenhofergesellschaft, GSF Neuherberg or MPI-Institutes are using BIO-SYS-instruments. Many private or Government research-institutes like Institute for Tropic-Medicine, Hamburg, National Animal Health Research Institute Greifswald-Insel Riems, Jena and many others are using BIO-SYS-instruments as well.

Pharmaceutical:
Global German manufacturers of pharmaceutical products like Bayer, BASF, Aventis, Boehringer, Thomae as well as companies like Roche, Novartis and others regularly apply BIO-SYS-Counters for genetic-toxicological and micro-biological colony-count.

Medical Research:
In 1999 BIO-SYS introduced the BIOREADER for Elispot-Assays and Colony-Forming-Ability-Test. Meanwhile more than 300 Readers/Counters have been established worldwide:

* University Clinique Institutes Bonn, Essen, Regensburg and Homburg
* LMU, Munich and many other German institutes

International:
* CHUV, Clinique Institute Ludwig / Lausanne
* Institute Pasteur / Paris
* Biochemic, Bellinzano,
* UM Baltimore,
* UVa Charlottesville
* CDC, Center of AIDS / Beijing
* John Curtin School of Medical Science, Australian National University / Canberra
* University Medical Center / Leiden
* Barbara Davis Center for Childhood Diabetes University of Colorado / Denver

Quality-Control:
Several private and Government Food-Control-Laboratories are continuous and satisfied customers of BIO-SYS systems.

* SGS Institut Fresenius GmbH / Taunusstein
* Forschungsinstitut Hohenstein / B?nnigheim

International success:
BIO-SYS’ is represented internationally in the following countries:

Austria, Switzerland, China, France, India, Italy, Singapore and the USA (ImmunoBioSys Inc.)